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Add The New York Post on Google I’ve covered K-beauty for years, and I’ve never seen Medicube’s One Day Exosome Shot 2000 67% off.
I’ve reviewed the product — and nearly all of Medicube — in both South Korea and the U.S., and the brand reigns supreme as one of the most effective K-beauty names for achieving a refined, dull-reversing glow. So, seeing one of its most talked-about treatment products at such a steep discount ahead of Prime Day (which is returning on Oct. 6, BTW) immediately caught my attention.
The Medicube One Day Exosome Shot 2000 targets the skin concerns I hear about constantly: visible pores, uneven texture and a complexion that has lost its smoothness and brightness. The formula uses Medicube’s spicule technology, which creates the prickly, tingling sensation that has become one of the product’s defining features.
I’ve tested plenty of products that promise smoother, brighter skin, and Medicube consistently stands out for the visible difference it can make in how polished my complexion looks. The brand has built a following around products that target texture, pores and dullness without making skincare feel overly complicated.
The One Day Exosome Shot 2000 is designed as an at-home treatment for improving the look of skin texture and pores. It’s not a substitute for professional microneedling, despite the comparisons that sometimes surround spicule-based skincare. Instead, it offers a more intensive step than a typical serum or essence, with the spicules creating a noticeable sensation as you apply it.
The formula also contains ingredients including niacinamide, panthenol and adenosine, along with lactobacillus extracellular vesicles. Together, the ingredients are aimed at supporting a smoother, brighter-looking complexion while the spicule technology gives the product its treatment-focused edge.
The sensation is the biggest consideration. This is not a barely-there serum that disappears onto the skin without you noticing. The spicules can feel prickly, so I would be more cautious about using it on particularly sensitive or already irritated skin. However, it’s great on my sensitive skin, and I use it about once a week at most for a facial-esque treat-myself moment.
At 67% off, the One Day Exosome Shot 2000 is now considerably more tempting to try, particularly because this is one of the best early Prime Day beauty deals I’ve seen.
Medicube has earned its reputation in my skincare routine through products that deliver the refined, luminous finish I associate with the best of K-beauty. With the One Day Exosome Shot 2000 currently marked down this heavily, it is a standout opportunity to try one of the brand’s more intensive approaches to smoother, brighter-looking skin.
After reviewing this retinol product for anti-aging, my skin has never felt brighter or tighter (in the best way). My sensitive skin doesn’t love retinol that much, but I use this as part of my routine about once a week now.
More than 20,000 shoppers purchase it monthly, more than 56,000 rave about it and this anti-aging cream is now only $7.
Want a red light mask without the sky-high prices? Luckily, this top-rated device from iRestore is $400 off ahead of Prime Day.
Prime Big Deal Days — fondly known as October Prime Day — is Amazon’s biggest fall sale, offering massive discounts before the holiday rush of Black Friday and Cyber Monday. October Prime Day runs from Tuesday, Oct. 6 to Wednesday, Oct. 7, 2026.
Prime Day and Prime Big Deal Days are both Prime member-exclusive seasonal sales with massive discounts on rotating bestsellers. Unlike July’s Prime Day, Prime Big Deal Days runs every October as a precursor to the busy holiday season, allowing shoppers to start saving on gift shopping early.
October Prime Day is exclusively available to Prime members. However interested shoppers can grab a 30-day free trial to try Prime, and its many benefits with no strings attached, and gain access to exclusive deals and the convenience of fast, free shipping.
From reporting on Amazon sales for years, we can tell you for certain that Amazon’s October Prime Day is the ideal time to save on big-ticket tech, Amazon devices, gift-worthy clothing and beauty and skincare staples, household essentials and many more Amazon best-sellers.
Every Prime Day sale is a great chance to score deals on thousands of best-sellers, top tech and appliances and every day essentials, but Amazon’s October event also has great pre-holiday discounts on gifts. Our team diligently sorts through all the offers to find the very best items to grab on sale.
Already wondering when Amazon’s next Prime Day is? We expect Prime Day to return in summer 2027, but anticipate just-as-good (if not better) deals coming this Black Friday and Cyber Monday. Follow Post Wanted’s around-the-clock coverage, and you’ll be the first to know about headline-worthy sales. Click here to find all of the best deals.
This article was written by Victoria McDonnell, New York Post Commerce Journalist & Content Strategist, who has spent countless hours researching, testing hundreds of products and comparing the latest makeup, skincare, hair and beauty items and trends to determine what’s truly worth your hard-earned cash. She evaluates formulas, textures, ingredients and more, in addition to consulting medical and industry experts. Some of Victoria’s latest conquests include testing the best sheet masks on the market, and a rinse-and-repeat review of the best shampoos for all hair types and budgets. Victoria, who received a beauty industry essentials certification from the Fashion Institute of Technology, has been creating shopping guides for the New York Post since 2021 and previously held positions at Insider Reviews and CNN Underscored.
Looking for a headline-worthy haul? Keep shopping Post Wanted.
