Brock Purdy of the 49ers passes the ball during the 2026 NFL Melbourne Game between the Los Angeles Rams and the San Francisco 49ers at the Melbourne Cricket Ground. JOEL CARRETT/EPA/Shutterstock See more of our coverage in your search results.
Add The New York Post on Google Dolphins vs. 49ers traders can use the Kalshi promo code NYPMAX to trade $25 and receive a $25 bonus.
The 49ers return from their season-opening trip to Australia for their Levi’s Stadium debut after dismantling the Rams, 27-7. Meanwhile, Miami opened up with a 27-13 loss to Las Vegas.
San Francisco is the biggest favorite on the Week 2 board at 13.5 points, with the spread jumping three points from its 10.5-point opener.
You can sign up for the prediction market and trade on any Week 2 NFL game on Sunday.
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Kyle Shanahan could lean heavily on the ground game after San Francisco rushed for 174 yards on 30 carries against the Rams, while Miami surrendered 130 rushing yards to Las Vegas.
The biggest mismatch may come in the trenches. Malik Willis was sacked five times in his Dolphins debut and now has to deal with Nick Bosa and a San Francisco defense that held Matthew Stafford and the Rams scoreless over the final three quarters.
San Francisco also forced two turnovers in Week 1 after finishing bottom six in the NFL in takeaways per game last season, giving Raheem Morris’ aggressive defense an opportunity to build on its fast start against an undermanned Miami offense.
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Sean Treppedi handicaps the NFL, NHL, MLB and college football for the New York Post. He primarily focuses on picks that reflect market value while tracking trends to mitigate risk.
