Rams defensive end Aaron Donald (99) at practice at the Rams Practice Facility. IMAGN IMAGES via Reuters Connect See more of our coverage in your search results.
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It’s Super Bowl or bust for the Rams, who kick off their 2026 quest against the 49ers on “Thursday Night Football.”
Polymarket traders are projecting the Rams to have a 66 percent chance to win, while they are laying 3.5 points on the spread.
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The Rams enter the season as the NFL’s most complete team after going 12-5 last year and strengthening their biggest weakness in the secondary.
With an elite offense and additions like Trent McDuffie, Jaylen Watson and Myles Garrett, they have the elite upside, though age, depth and a brutal early schedule are concerns.
The 49ers also won 12 games last season despite major defensive injuries, but they face another wave of health concerns entering 2026.
Their strong divisional outlook and ability to survive without Brock Purdy give them a high floor, though last year’s one-score record and special-teams luck make regression a real possibility.
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Sean Treppedi handicaps the NFL, NHL, MLB and college football for the New York Post. He primarily focuses on picks that reflect market value while tracking trends to mitigate risk.
